| Tumors - Patients |
| Lung adenocarcinoma |
1,199 |
| Acute myeloid leukemia |
1,134 |
| Lung squamous cell carcinoma |
744 |
| Colorectal adenocarcinoma |
2,434 |
| Ependymoma |
57 |
| Non-hodking lymphoma |
3,190 |
| Mesothelioma |
162 |
| Bladder cancer |
767 |
| Renal clear cell carcinoma |
1,343 |
| Breast adenocarcinoma |
2,515 |
| Prostate adenocarcinoma |
1,401 |
| Non small cell lung cancer |
1,943 |
| Stomach adenocarcinoma |
793 |
| Cervix squamous cancer |
308 |
| High-grade Glioma |
1,201 |
| Nasopharyngeal cancer |
278 |
| Small-cell lung cancer |
388 |
| Endometrial cancer |
606 |
| Renal papillary cell carcinoma |
320 |
| Osteosarcoma |
112 |
| Lower grade glioma |
1,095 |
| Diffuse large B-cell lymphoma |
303 |
| Sarcoma |
886 |
| Ewing's sarcoma |
235 |
| Thyroid adenocarcinoma |
1,018 |
| Neuroblastoma |
692 |
| Skin basal cell carcinoma |
126 |
| Adrenocortical carcinoma |
71 |
| Pheochromocytoma and paraganglioma |
60 |
| Ovary cancer |
767 |
| Acute lymphoblastic leukemia |
1,050 |
| Multiple myeloma |
73 |
| Medulloblastoma |
514 |
| Cholangiocarcinoma |
668 |
| Chronic Lymphocytic Leukaemia |
948 |
| Glioblastoma |
1,068 |
| Chromophobe renal cell carcinoma |
114 |
| Wilms tumor |
291 |
| Male germ cell tumor |
77 |
| Any Tumor Type |
36,195 |
|
| Mutations |
| Mutations (in total) |
19,801,769 |
| Mutations in reference proteome |
10,987,888 |
| Mutations with structural annotation |
4,216,868 |
| - Surface mutations |
3,490,739 |
| - Buried mutations |
728,236 |
| - Interface mutations |
665,319 |
|
| Proteins |
| Proteins in the human proteome |
20,596 |
| Proteins affected by somatic mutations |
19,120 |
| Mutated proteins with structural data |
12,852 |
| - Mutated proteins with complete structures |
2,449 |
| - Mutated proteins with complete models |
3,029 |
| - Mutated proteins with partial struct/models |
7,374 |
| Mutated proteins w/o structural data |
6,268 |
| Mutated proteins in the interactome |
15,592 |
| Mut. proteins with struct. data in the interactome |
11,231 |
| Proteins affected by interaction mutations |
7,353 |
|
| Interactions |
| Interactions in the human binary interactome |
136,329 |
| Interactions affected by somatic mutations |
15,690 |
| Interactions with structural data |
15,984 |
| - Interactions with exp. structures |
8,359 |
| - Interactions with global models |
5,311 |
| - Interactions with domain-domain models |
2,314 |
| Interactions w/o structural data |
120,345 |
|
|
